b'SPONSORED CONTENTWhat is 2-Fucosyllactose? By Seth Kaelin2-Fucosyllactose (2-FL) is a human milktions of Bifidobacteria as the microbialGI. Because of this similarity, 2-FL oligosaccharide (HMO), which servespopulation develops, and infants aremolecules can act as binding decoys to as a prebiotic in the human digestivecontinually exposed to new microbesbiological toxins and external microor-system. [1]HMOs are the first prebioticfrom the environment.[7] ganisms that are known disruptors of compounds that a breastfed newbornthe GI to prevent them from binding will encounter, the prebiotic designedHMOs support the barrier in thesurface-bound sugars. [3, 13, 14]This activity by nature, for humans. Discovered inlower GI minimizes the amount of external the 1950s, 2-FL is the most abundantHealthy gut function relies on a propermicroorganisms such as norovirus, HMO found in breast milk, making upGI barrier between the body andCampylobacter jejuni, and enterotoxi-30 percent of all breast milk HMOs. [2] the interior space that makes up thegenic E. coli launching infections and All HMOs are prebiotics, but not digestive tract, called the lumen. The GItriggering the inflammatory response.all prebiotics are HMOs barrier is made up of many layers: In breastfed infants, this binding decoy HMOs avoid metabolism by digestive A luminal mucosal barrier mechanism works as an extension of enzymes until they reach the lower GI, Microbial inhabitants lining cells in the GI immune system. Thus, it is not surprising that there are lower markers which allows beneficial microorganismsthe lumen for inflammation in infants fed formula like Bifidobacteria to then break them [3, 4]with added HMOs compared to a more down through fermentation.2-FL isA layer of mucus produced bya unique prebiotic in that only certaingoblet cells traditional formula with prebiotics from species, primarily Bifidobacteria, can cows milk. [15]A chemical barriermetabolize it. Thus, 2-FL is a selective A physical barrier of intestinal In addition to acting as an importantfeeding source for Bifidobacteria. epithelial cells held together by component of a newborns microbiome [3] Other gut microbes, includingtight junctions and healthy GI tract, 2-FL also works as opportunistic pathogens, have to relya targeted prebiotic for adults due to its [5][8]on non-2-FL sources of nourishment. An immunological barrierunique tie to Bifidobacteria. For adults, Babies are born with a limited numberStress, microbial invaders, antibiotic use,2-FL supports short-term feeding of of microbes encompassing their GIand development of chronic conditionsbeneficial Bifidobacteria in times of GI microbiome. When HMOs are fed tocan disrupt the intestinal lining. HMOsstress and for individuals deficient in infants through breastfeeding, theylike 2-FL stimulate the developmentBifidobacteria populations looking to facilitate the growth of a GI tractand maintenance of a well-functioningincrease microbiome diversity. [16] dominated by Bifidobacteria. MothersGI barrier, both during development who secrete more 2-FL in breast milkand in cases of GI inflammation[9-12] . For a list of references in this article please will in turn produce larger populationsvisit WholisticMatters.com, Powered by of Bifidobacteria for their babies. [6] 2-FL acts as a binding decoy Standard Process: wholisticmatters.com/Microbiomes of infants fed breast milk2-FL is similar in structure to certainfood-for-beneficial-bacteria-2fl-a- are also able to retain higher propor- binding sites on cells of the lowerhuman-milk-oligosaccharidePower UP and expect moreThe nations leading malpractice Partner with the best.insurance for 25% less. Learn to expect more from your therapy laser with the powerful Contact us today to see how much a switch could save you. LightForce i-Series. Expect consistent clinical outcomes. Expect more patients and greater incomes. Expect a partner chiropreferred.com/ANJCSummer committed to your success. With LightForce, expect more.833.4CHIROS|SOLUTIONS@CHIROPREFERRED.COM DOWNLOAD the FREE Laser Therapy FAQ eBook at ChiroPreferred is the marketing name used to refer to the chiro-related products and services offered by MedPro Group. 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